Sure, Avandia™ May Increase Your Chance Of A Heart Attack By 43 Percent, But That Doesn't Mean It Doesn't Do Good Things.

Without Avandia ™ for instance, fat models might never be able to find work:



Then they wouldn't be able to eat, which means they would lose weight, and then maybe be able to find work. I think that's called an irony cycle.

Oh, and to those who say that there is no difference between Avandia and Actos, I call bullshit on you.

Results of a head-to-head comparison of two insulin-sensitizing agents, pioglitazone (Actos®, Takeda/Lilly) and rosiglitazone (Avandia®, GlaxoSmithKline), show that although both are equally effective in achieving glycemic control in patients with type 2 diabetes mellitus and dyslipidemia, they appear to have differential effects on lipids. Relative to rosiglitazone, pioglitazone improved triglycerides, HDL-C, non-HDL-C, and LDL particle concentration and size, although both agents increased LDL levels.

I'll use my magical drugmonkey science nerd to English translator:

This study showed that both Avandia and Actos are equally effective at decreasing a persons blood sugar. Both raised LDL ("bad" cholesterol) BUT........Actos raised HDL ("good" cholesterol) and decreased Triglycerides ("Blood fats"), while Avandia raised triglycerides.

Now I'll use my super magical science nerd to Homer Simpson level English translator:

Actos had better effects on people's cholesterol than Avandia.

This study was done in 2004, and today we are hearing of a possible link between Avandia and an increased risk of heart disease. Go figure. I think that would be called a non-irony cycle.